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    The effect of the osteopathic thoracic lymphatic pump technique on salivary secretory immunoglobulin A levels in adults with recurrent upper respiratory tract complaints

    Blut, Dominik Patricio Ferdinand

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    Dominik Blut_2015-06-17.pdf (2.272Mb)
    Date
    2015-06-17
    Citation:
    Blut, D. P. F. (2015). The effect of the osteopathic thoracic lymphatic pump technique on salivary secretory immunoglobulin A levels in adults with recurrent upper respiratory tract complaints. An unpublished research project submitted in partial fulfilment of the requirements for the degree of Master of Osteopathy, Unitec Institute of Technology.
    Permanent link to Research Bank record:
    https://hdl.handle.net/10652/3109
    Abstract
    BACKGROUND: Low levels of salivary SIgA have been associated with upper respiratory tract infection, oral ulceration and systemic diseases. Osteopathic Manipulative Treatment has been shown to have a positive effect on salivary SIgA levels. OBJECTIVE: This single case study aimed to determine changes in salivary SIgA concentration and secretion rate in response to a single 7-minute intervention of the osteopathic thoracic lymphatic pump in four male subjects who indicated suppressed mucosal immunity identified by recurrent upper respiratory tract infection and oral ulceration. METHODS: On a single day a total of nine saliva samples were collected per participant via oral swab, including four samples pre-, one peri- and four post-intervention. Participant results were analysed individually with group statistics reported. RESULTS: At baseline all participants showed suppressed levels of salivary SIgA concentrations with an average of 58.03 μg/mL (<79.26 μg/mL). Post-intervention Salivary SIgA concentrations increased in three participants [Effect size (ES) = 1.74 - 2.71]. On average salivary SIgA concentrations increased to 72.73 μg/mL (25.3%). Salivary SIgA secretion rates showed no clear pattern of change (ES = -1.82 to 1.96). On average salivary SIgA secretion rates increased from 23.8 μg/min to 24.4 μg/min (5.9%). The mean effect size for salivary SIgA secretion rates baseline to post-intervention was d=0.05. CONCLUSION: This study showed some indication of an overall trend for an increase in salivary SIgA concentration. Changes in salivary SIgA secretion rate were inconsistent and the therapeutic benefit of the thoracic lymphatic pump in participants with a suppressed mucosal immune function remains unclear.
    Keywords:
    antibodies, aphthous ulcers, recurrent, biomarkers, manual immunomodulatory therapy, osteopathic medicine, serology, immune system, thoracic lymphatic pump technique, lymphatic pump technique, immunoglobulin A levels
    ANZSRC Field of Research:
    110499 Complementary and Alternative Medicine not elsewhere classified, 110203 Respiratory Diseases
    Degree:
    Master of Osteopathy
    Supervisors:
    Bacon, Catherine
    Rights:
    This digital work is protected by copyright. It may be consulted by you, provided you comply with the provisions of the Act and the following conditions of use: Any use you make of these documents or images must be for research or private study purposes only, and you may not make them available to any other person. You will recognise the author's and publishers rights and give due acknowledgement where appropriate.
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